Endocrine Abstracts

Background: The prevalence of the diabetes mellitus is rapidly increasing particularly in developing countries. For effective management of diabetes, patients must be actively involved in their care. The aim of the study was to assess the knowledge and self-care practices and contribution of the education to this knowledge level and glycemic control.Material methods: We formed patients groups consisting of 15 to 30 diabetic patients. Firstly, patients su...

Introduction: Thyroid papillary carcinomas originate from thyroid follicular epithelia and are the most frequent thyroid differentiated carcinomas. Medullary thyroid carcinomas originate from thyroid parafollicular C cells and %25 are a component of Multiple Endocrine Neoplasia (MEN) syndromes. Co-incidence of the two condition on the same patient is so rare.Case: 78 years old female patient who has had simple goiter for 10 years, was investigated about ...

Introduction: Differentiated thyroid carcinomas (DTC) are originated from thyroid follicular epithelial cells and comprises %90 of all thyroid carcinomas. Researches indicate that sorafenib is more efficacious than other chemotherapeutic agents on metastatic iodide refractory DTCs.Material and methods: In our center, between 2013 and 2015, sorafenib was applied to six patients who had iodide refractory metastatic DTC. Five of the patients were female. Th...

Introduction: Primary squamous cell carcinoma (PSCC) of thyroid is a rare type of thyroid malignancies because thyroid gland lacks squamous epithelium. It is seen in <1% of all thyroid malignancies. During last 30 years only about 90 cases were published. PSCC is an aggressive tumour as well as rare.Case report: We present a 60-year-old female who had been followed up for multiple nodules in thyroid in our outpatient clinic for 2 years. Her serum fre...

Classic thyroid hormone resistance (THR) occurs per every 400 000 live birth. THR should be considered along with TSH-producing adenomas when normal or high levels of TSH not consistent with hyperthyroidism is present. A 45-year-old female patient who was operated three times for multinodulary goitre had been treated with L-thyroxine. Mamillary biopsy had performed after detection of mass localized in right breast by mammography performed during regular follow-u...

Introduction: Primary thyroid lymphomas are rare cancers and account 1–5% of all thyroid cancers and 3% of all extranodal non hodgkin lymphomas (NHLs). We aimed to present cases of thyroid lymphoma encountered in our clinic.Case 1: A 54-year-old female patient admitted with pain and swallow on the cervical region. In ultrasonographic (USG) thyroid examination, it was found that both thyroid lobes were very large with routh parenchyme consis...

Background: Incretin-based therapy is increasingly used in the management of type 2 diabetes mellitus. Although dipeptidyl peptidase-4 inhibitors (gliptins) are well tolerated, side effects can be observed in various body systems. Here we report three cases of drug-induced skin eruption with strong itching of the gliptins plus metformin combination therapy.Case reports: A 59-year-old woman and a 57-year-old man, who had been using vildagliptin plus metfo...

Aim: To evaluate prevalence of erectile dysfunction (ED) in patients with type 2 diabetes in relation to the cardiovascular risk factors.Methods: A total of 116 males including type 2 diabetic patients (n=68, mean age: 56.7 (5.8) years) and age-matched healthy controls (n=48, mean age: 57.0 (6.6) years) were included to study. Concomitant hypertension, hyperlipidemia, and coronary artery disease (CAD) were recorded in each subject along...

Aim: Erectile dysfunction (ED) has been reported to occur more commonly in diabetes than general population with the prevalence rate varies widely from 35 to 75%. Patients with diabetes was also shown to have much earlier onset of ED and more severe form of the disease associated with a poorer quality of life. We aimed to evaluate association of ED with diabetes related complications in patients with type 2 diabetes in our study.Methods: In a total of 68...

Background: Although very rare, insulinomas are the most commonly occurring endocrine tumor of the pancreas. The aim of this study was to review the clinical presentation, diagnostic approach and management of patients with an insulinoma.Methods: 22 insulinoma patients, with an age range of 20–79, were included and evaluated according to their clinical presentation, blood biochemistry, imaging studies, operative management, pathological manifestatio...